Researcher · Evidence Profile

A. John Rush

A. John Rush appears on 9 studies of vagus nerve stimulation catalogued in our evidence database, with a focus on Depression.

9
Studies
1
Conditions
3
RCT / SR-MA
2
Stim. types

Conditions researched

Depression9

Evidence-tier mix

Randomised controlled trial3
Cohort / observational5
Case series / report1

The studies

9 studies · strongest evidence first

  1. Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial

    Rush et al. · Brain stimulation · 2025 · n = 493

    RCTsDepressiontaVNS
    Read summary & citations →DOI

  2. Vagus nerve stimulation in treatment-resistant depression: A one-year, randomized, sham-controlled trial

    Conway et al. · Brain stimulation · 2025

    RCTsDepressiontaVNS
    Read summary & citations →DOI

  3. Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial

    Rush et al. · Biological Psychiatry · 2005 · n = 235

    RCTsDepressioniVNS
    Read summary & citations →DOI

  4. Prognostic and Prescriptive Predictors of Treatment Response to Adjunctive VNS Therapy in Major Depressive Disorder: A RECOVER Trial Report

    Aaronson et al. · The Journal of Clinical Psychiatry · 2025 · n = 493

    observational studiesDepressioniVNS
    Read summary & citations →DOI

  5. The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry

    McAllister-Williams et al. · International journal of bipolar disorders · 2020 · n = 156

    observational studiesDepressioniVNS
    Read summary & citations →DOI

  6. A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression

    George et al. · Biological psychiatry · 2005 · n = 329

    observational studiesDepressioniVNS
    Read summary & citations →DOI

  7. Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study

    Rush et al. · Biological psychiatry · 2005 · n = 205

    observational studiesDepressioniVNS
    Read summary & citations →DOI

  8. Two-year outcome of vagus nerve stimulation (VNS) for treatment of major depressive episodes

    Nahas et al. · The Journal of clinical psychiatry · 2005 · n = 59

    observational studiesDepressioniVNS
    Read summary & citations →DOI

  9. Clinical issues in considering vagus nerve stimulation for treatment-resistant depression

    Rush et al. · Experimental neurology · 2009

    narrative reviewsDepressioniVNS
    Read summary & citations →DOI
← All researchersBrowse the full evidence database →

Stay Current with the Research

Join researchers and practitioners exploring the science of vagus nerve stimulation. Receive curated research summaries and evidence updates.

No spam. Unsubscribe at any time. We respect your privacy.