A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression
George MS, Rush AJ, Marangell LB, Sackeim HA, Brannan SK, Davis SM, Howland R, Kling MA, Moreno F, Rittberg B, et al.
Biological Psychiatry · 2005
Key finding
Nonrandomized comparison of VNS plus treatment-as-usual (n=205) vs treatment-as-usual alone (n=124) showed higher 12-month HRSD-24 response (27% vs 13%) for VNS.
- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 329
Cite this study
George, M. S., Rush, A. J., Marangell, L. B., Sackeim, H. A., Brannan, S. K., Davis, S. M., Howland, R., Kling, M. A., Moreno, F., Rittberg, B., Dunner, D., Schwartz, T., Carpenter, L., Burke, M., Ninan, P., & Goodnick, P. (2005). A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression. Biological Psychiatry, 58(5), 364-373. https://doi.org/10.1016/j.biopsych.2005.07.028
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Summary by Vagus Research. Always consult the primary source for the authoritative record.