A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression
George MS, Rush AJ, Marangell LB, Sackeim HA, Brannan SK, Davis SM, Howland R, Kling MA, Moreno F, Rittberg B, et al.
Biological Psychiatry · 2005
Key finding
Nonrandomized comparison of VNS plus treatment-as-usual (n=205) vs treatment-as-usual alone (n=124) showed higher 12-month HRSD-24 response (27% vs 13%) for VNS.
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- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 329
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Cite this study
George, M. S., Rush, A. J., Marangell, L. B., Sackeim, H. A., Brannan, S. K., Davis, S. M., Howland, R., Kling, M. A., Moreno, F., Rittberg, B., Dunner, D., Schwartz, T., Carpenter, L., Burke, M., Ninan, P., & Goodnick, P. (2005). A one-year comparison of vagus nerve stimulation with treatment as usual for treatment-resistant depression. Biological Psychiatry, 58(5), 364-373. https://doi.org/10.1016/j.biopsych.2005.07.028
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