The efficacy and safety of transcutaneous auricular vagus nerve stimulation in the treatment of depressive disorder: a systematic review and meta-analysis of randomized controlled trials
Lyu Z, Chen Y, Zhu Z, Luo X, Cui Y, Xie J, Chen Z, Liu J, Wu X, Bulloch G, et al.
Journal of Affective Disorders · 2023
Key finding
Pooled analysis of RCTs found that taVNS significantly reduced depression scores compared to sham stimulation, with moderate effect sizes and fewer side effects than antidepressants.
- Condition
- Depression
- Stimulation
- taVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
Cite this study
Lyu, Z., Chen, Y., Zhu, Z., Luo, X., Cui, Y., Xie, J., Chen, Z., Liu, J., Wu, X., Bulloch, G., & Meng, Q. (2023). The efficacy and safety of transcutaneous auricular vagus nerve stimulation in the treatment of depressive disorder: a systematic review and meta-analysis of randomized controlled trials. Journal of Affective Disorders, 336, 15-24. https://doi.org/10.1016/j.jad.2023.05.040
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Summary by Vagus Research. Always consult the primary source for the authoritative record.