
Popular science — flagship
The Great Nerve
The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes
Kevin J. Tracey, MD
2025 · Penguin Life
The definitive current title, written by the neurosurgeon who discovered the inflammatory reflex — the mechanism linking vagal signalling to immune control. Tracey traces the science from accidental lab discovery to human trials, showing how electrical stimulation of the vagus is being tested to reverse rheumatoid arthritis, IBD, and other inflammatory disease without drugs. Crucially for an evidence-based audience, he separates fact from hype on the popular 'stimulation' practices — ice baths, breathwork, meditation — measured about their potential without overselling. The natural anchor for the collection.








