Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study
Rush AJ, Sackeim HA, Marangell LB, George MS, Brannan SK, Davis SM, Lavori P, Howland R, Kling MA, Rittberg B, et al.
Biological Psychiatry · 2005
Key finding
Over 12 months of open follow-up of the D-02 cohort, HRSD-24 scores fell significantly with a 27.2% response rate and 15.8% remission rate.
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- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 205
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Cite this study
Rush, A. J., Sackeim, H. A., Marangell, L. B., George, M. S., Brannan, S. K., Davis, S. M., Lavori, P., Howland, R., Kling, M. A., Rittberg, B., Carpenter, L., Ninan, P., Moreno, F., Schwartz, T., Conway, C., Burke, M., & Barry, J. J. (2005). Effects of 12 months of vagus nerve stimulation in treatment-resistant depression: a naturalistic study. Biological Psychiatry, 58(5), 355-363. https://doi.org/10.1016/j.biopsych.2005.05.024
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