The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry
McAllister-Williams RH, Sousa S, Kumar A, Greco T, Bunker MT, Aaronson ST, Conway CR, Rush AJ
International Journal of Bipolar Disorders · 2020
Key finding
In bipolar treatment-resistant depression, adjunctive VNS plus treatment as usual (n=97) produced better 5-year response and remission outcomes than treatment as usual alone (n=59).
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- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 156
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Cite this study
McAllister-Williams, R. H., Sousa, S., Kumar, A., Greco, T., Bunker, M. T., Aaronson, S. T., Conway, C. R., & Rush, A. J. (2020). The effects of vagus nerve stimulation on the course and outcomes of patients with bipolar disorder in a treatment-resistant depressive episode: a 5-year prospective registry. International Journal of Bipolar Disorders, 8(1). https://doi.org/10.1186/s40345-020-0178-4
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