Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study
Rush AJ, George MS, Sackeim HA, Marangell LB, Husain MM, Giller C, Nahas Z, Haines S, Simpson RK, Goodman R
Biological Psychiatry · 2000
Key finding
Open-label pilot in 30 treatment-resistant patients showed a 40% response rate on the HDRS-28, suggesting an antidepressant effect of VNS.
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- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- 30
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Cite this study
Rush, A. J., George, M. S., Sackeim, H. A., Marangell, L. B., Husain, M. M., Giller, C., Nahas, Z., Haines, S., Simpson, R. K., & Goodman, R. (2000). Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study. Biological Psychiatry, 47(4), 276-286. https://doi.org/10.1016/s0006-3223(99)00304-2
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