Controlled Clinical TrialiVNS

Prenatal electroacupuncture modulates maternal-fetal immune activation via a brain-to-splenic signal

Zhang Z, Lin W, Yan J, Wang X, Wang J, Wang F, He T, Xu J, Xia Y, Chen Y

Cell Reports · 2025

Key finding

These findings position the brain-spleen axis as a promising therapeutic target and support prenatal ES as a viable non-pharmacological strategy for preventing MIA-related complications.

Condition
Schizophrenia
Stimulation
iVNS
Evidence tier
Controlled Clinical Trial
Participants
View on DOI

Cite this study

Zhang, Z., Lin, W., Yan, J., Wang, X., Wang, J., Wang, F., He, T., Xu, J., Xia, Y., & Chen, Y. (2025). Prenatal electroacupuncture modulates maternal-fetal immune activation via a brain-to-splenic signal. Cell Reports, 44(11), 116576. https://doi.org/10.1016/j.celrep.2025.116576

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