Efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with treatment-resistant schizophrenia with predominantly negative symptoms: a randomized clinical trial and efficacy sensitivity biomarkers
Cui Y, Sun J, Zhang B, Guo T, Zhang S, Li Z, Chen Y, Su M, Wu D, Wu J, et al.
Molecular Psychiatry · 2025
Key finding
An RCT of taVNS for the persistent negative symptoms of treatment-resistant schizophrenia (detailed outcomes not in the indexed abstract).
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- Condition
- Schizophrenia
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 50
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Cite this study
Cui, Y., Sun, J., Zhang, B., Guo, T., Zhang, S., Li, Z., Chen, Y., Su, M., Wu, D., Wu, J., Wang, Q., Yuan, Y., Wang, J., Tian, Q., He, F., Wu, L., Li, X., Gong, Y., & Qin, W. (2025). Efficacy and safety of transcutaneous auricular vagus nerve stimulation for patients with treatment-resistant schizophrenia with predominantly negative symptoms: a randomized clinical trial and efficacy sensitivity biomarkers. Molecular Psychiatry, 30(11), 5437-5447. https://doi.org/10.1038/s41380-025-03132-8
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Summary by Vagus Research. Always consult the primary source for the authoritative record.