Randomised Controlled TrialtaVNSn = 72

Transcutaneous auricular vagus nerve stimulation for chronic insomnia disorder: a randomized clinical trial

Zhang S, Zhao Y, Qin Z, Han Y, He J, Zhao B, Wang L, Duan Y, Huo J, Wang T, et al.

JAMA Network Open · 2024

Key finding

Active taVNS achieved a mean PSQI reduction of 8.2 points versus 3.9 for sham (Cohen's d = 1.2) in chronic insomnia, with benefits sustained over 20 weeks and no serious adverse effects.

Condition
Sleep
Stimulation
taVNS
Evidence tier
Randomised Controlled Trial
Participants
72
View on DOI

Cite this study

Zhang, S., Zhao, Y., Qin, Z., Han, Y., He, J., Zhao, B., Wang, L., Duan, Y., Huo, J., Wang, T., Wang, Y., & Rong, P. (2024). Transcutaneous auricular vagus nerve stimulation for chronic insomnia disorder: a randomized clinical trial. JAMA Network Open, 7(12), e2451217. https://doi.org/10.1001/jamanetworkopen.2024.51217

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