Baseline functional connectivity of the basal forebrain-cortical circuit predict taVNS treatment response in primary insomnia: a randomized controlled trial and fMRI study
Qi M, Huang Y, Mai R, Yan Z, Xu B, Liu B, Zhang Y
BMC Medicine · 2025
Key finding
Sixty-seven patients completed the study (33 real taVNS, 34 sham taVNS).
- Condition
- Depression
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
Cite this study
Qi, M., Huang, Y., Mai, R., Yan, Z., Xu, B., Liu, B., & Zhang, Y. (2025). Baseline functional connectivity of the basal forebrain-cortical circuit predict taVNS treatment response in primary insomnia: a randomized controlled trial and fMRI study. BMC Medicine, 23(1). https://doi.org/10.1186/s12916-025-04126-7
Related studies in Depression
Long-term efficacy and safety of vagus nerve stimulation in treatment-resistant depression: A systematic review
Rosson et al. · Journal of Affective Disorders · 2026 · Systematic Review / Meta-Analysis
The efficacy and safety of transcutaneous auricular vagus nerve stimulation in the treatment of depressive disorder: a systematic review and meta-analysis of randomized controlled trials
Tan et al. · Journal of Affective Disorders · 2023 · Systematic Review / Meta-Analysis
Adjunctive Vagus Nerve Stimulation for Treatment-Resistant Depression: a Quantitative Analysis
Zhang et al. · The Psychiatric quarterly · 2020 · Systematic Review / Meta-Analysis
Vagus Nerve Stimulation for Depression: A Systematic Review
Lv et al. · Frontiers in psychology · 2019 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.