Transcutaneous auricular vagus nerve stimulation to treat narcolepsy type 1 (TARGET-NT1): A two-arm, randomised, sham-controlled trial
Pan Y, Zhang Y, Xu Z, Wei Z, Pan R, Hu G, Wang X, Yang L, Wu D, Zhang X, et al.
Neurotherapeutics · 2025
Key finding
In a double-blind, sham-controlled RCT (TARGET-NT1), taVNS as add-on therapy significantly improved daytime sleepiness and cataplexy symptoms in narcolepsy type 1.
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- Condition
- Sleep
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
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Cite this study
Pan, Y., Zhang, Y., Xu, Z., Wei, Z., Pan, R., Hu, G., Wang, X., Yang, L., Wu, D., Zhang, X., Wen, X., Qu, S., Li, C., Zhu, Z., Gao, Y., Shi, X., Zhu, Y., Wu, K., Wang, D., & Liu, Y. (2025). Transcutaneous auricular vagus nerve stimulation to treat narcolepsy type 1 (TARGET-NT1): A two-arm, randomised, sham-controlled trial. Neurotherapeutics, 22(4), e00604. https://doi.org/10.1016/j.neurot.2025.e00604
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