Controlled Clinical TrialtaVNS

Effects of transcutaneous auricular vagus nerve stimulation on brain functional connectivity of medial prefrontal cortex in patients with primary insomnia

Zhang S, He J, Meng H, Zhao B, Zhao Y, Wang Y, Li S, Wang L, Wu M, Chen Y, et al.

The Anatomical Record · 2021

Key finding

In patients with primary insomnia, taVNS altered medial-prefrontal-cortex functional connectivity, offering a neuroimaging correlate of its effect on sleep (mechanistic; clinical outcomes not the focus).

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Condition
Sleep
Stimulation
taVNS
Evidence tier
Controlled Clinical Trial
Participants
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Cite this study

Zhang, S., He, J., Meng, H., Zhao, B., Zhao, Y., Wang, Y., Li, S., Wang, L., Wu, M., Chen, Y., Xiao, X., Hou, L., Fang, J., & Rong, P. (2021). Effects of transcutaneous auricular vagus nerve stimulation on brain functional connectivity of medial prefrontal cortex in patients with primary insomnia. The Anatomical Record, 304(11), 2426-2435. https://doi.org/10.1002/ar.24785

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