A distinct biomarker of continuous transcutaneous vagus nerve stimulation treatment in major depressive disorder
Tu Y, Fang J, Cao J, Wang Z, Park J, Jorgenson K, Lang C, Liu J, Zhang G, Zhao Y, et al.
Brain Stimulation · 2018
Key finding
In mild-to-moderate MDD, treatment-induced insula connectivity changes after real versus sham taVNS correlated with and predicted improvement in 24-item HAMD scores.
- Condition
- Depression
- Stimulation
- taVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- 41
Cite this study
Tu, Y., Fang, J., Cao, J., Wang, Z., Park, J., Jorgenson, K., Lang, C., Liu, J., Zhang, G., Zhao, Y., Zhu, B., Rong, P., & Kong, J. (2018). A distinct biomarker of continuous transcutaneous vagus nerve stimulation treatment in major depressive disorder. Brain Stimulation, 11(3), 501-508. https://doi.org/10.1016/j.brs.2018.01.006
Related studies in Depression
Long-term efficacy and safety of vagus nerve stimulation in treatment-resistant depression: A systematic review
Rosson et al. · Journal of Affective Disorders · 2026 · Systematic Review / Meta-Analysis
The efficacy and safety of transcutaneous auricular vagus nerve stimulation in the treatment of depressive disorder: a systematic review and meta-analysis of randomized controlled trials
Tan et al. · Journal of Affective Disorders · 2023 · Systematic Review / Meta-Analysis
Adjunctive Vagus Nerve Stimulation for Treatment-Resistant Depression: a Quantitative Analysis
Zhang et al. · The Psychiatric quarterly · 2020 · Systematic Review / Meta-Analysis
Vagus Nerve Stimulation for Depression: A Systematic Review
Lv et al. · Frontiers in psychology · 2019 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.