Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit
Rosas-Ballina M, Olofsson PS, Ochani M, Valdés-Ferrer SI, Levine YA, Reardon C, Tusche MW, Pavlov VA, Andersson U, Chavan S, et al.
Science · 2011
Key finding
Thus, action potentials originating in the vagus nerve regulate T cells, which in turn produce the neurotransmitter, acetylcholine, required to control innate immune responses.
- Condition
- Inflammation
- Stimulation
- iVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- —
Cite this study
Rosas-Ballina, M., Olofsson, P. S., Ochani, M., Valdés-Ferrer, S. I., Levine, Y. A., Reardon, C., Tusche, M. W., Pavlov, V. A., Andersson, U., Chavan, S., Mak, T. W., & Tracey, K. J. (2011). Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit. Science, 334(6052), 98-101. https://doi.org/10.1126/science.1209985
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Summary by Vagus Research. Always consult the primary source for the authoritative record.