Vagus nerve stimulation in autoimmune conditions: a systematic review
Lombo LE, Tejada‐Perdomo JH, Ramos‐Castaneda JA, Garcia RG
ACR Open Rheumatology · 2025
Key finding
Across 12 clinical trials of VNS in autoimmune conditions, more than half found reductions in pro-inflammatory cytokines, with IL-6 most consistently reduced (6 of 7 studies).
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- Condition
- InflammationGut Health
- Stimulation
- iVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
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Cite this study
Lombo, L. E., Tejada‐Perdomo, J. H., Ramos‐Castaneda, J. A., & Garcia, R. G. (2025). Vagus nerve stimulation in autoimmune conditions: a systematic review. ACR Open Rheumatology, 7(12). https://doi.org/10.1002/acr2.70137
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