No consistent evidence for the anti-inflammatory effect of vagus nerve stimulation in humans: a systematic review and meta-analysis
Schiweck C, Sausmekat S, Zhao T, Jacobsen L, Reif A, Edwin Thanarajah S
Brain, Behavior, and Immunity · 2024
Key finding
Meta-analysis of 26 studies found no consistent evidence for anti-inflammatory effects of VNS in humans, highlighting the gap between compelling preclinical data and more equivocal clinical results.
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- Condition
- Inflammation
- Stimulation
- taVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- 1,135
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Cite this study
Schiweck, C., Sausmekat, S., Zhao, T., Jacobsen, L., Reif, A., & Edwin Thanarajah, S. (2024). No consistent evidence for the anti-inflammatory effect of vagus nerve stimulation in humans: a systematic review and meta-analysis. Brain, Behavior, and Immunity, 116, 237-258. https://doi.org/10.1016/j.bbi.2023.12.008
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