Systematic review and meta-analysis of vagus nerve stimulation in the treatment of depression: variable results based on study designs
Martin JLR, Martín-Sánchez E
European Psychiatry · 2012
Key finding
Meta-analysis of 14 studies found significant HAMD reduction and ~31.8% response in uncontrolled studies, but the single sham-controlled RCT (n=235) showed no significant difference versus sham.
- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
Cite this study
Martin, J. L. R., & Martín-Sánchez, E. (2012). Systematic review and meta-analysis of vagus nerve stimulation in the treatment of depression: variable results based on study designs. European Psychiatry, 27(3), 147-155. https://doi.org/10.1016/j.eurpsy.2011.07.006
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Summary by Vagus Research. Always consult the primary source for the authoritative record.