Non-invasive auricular vagus nerve stimulation in fibromyalgia: Impacts on autonomic function, central sensitization and pain catastrophizing
Lommano MG, Farah S, Bianchi B, Risa AM, Sarzi-Puttini P, Salaffi F, Di Carlo M
Joint Bone Spine · 2026
Key finding
Significant improvements were observed in total COMPASS-31 scores (P<0.05), particularly within the orthostatic (P<0.05), vasomotor (P<0.05), and pupillomotor (P<0.05) subdomains.
- Condition
- Fibromyalgia
- Stimulation
- taVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- —
Cite this study
Lommano, M. G., Farah, S., Bianchi, B., Risa, A. M., Sarzi-Puttini, P., Salaffi, F., & Di Carlo, M. (2026). Non-invasive auricular vagus nerve stimulation in fibromyalgia: Impacts on autonomic function, central sensitization and pain catastrophizing. Joint Bone Spine, 93(1), 105966. https://doi.org/10.1016/j.jbspin.2025.105966
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Summary by Vagus Research. Always consult the primary source for the authoritative record.