Randomised Controlled TrialtaVNS

Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial

Li S, Rong P, Wang Y, Jin G, Hou X, Li S, Xiao X, Zhou W, Wu Y, Liu Y, et al.

Neuromodulation: Technology at the Neural Interface · 2022

Key finding

The HAM-D17 scores were reduced in both treatment groups; however, there was no significant group-by-time interaction (95% CI: -0.07 to 0.15, p = 0.79).

Condition
Anxiety
Stimulation
taVNS
Evidence tier
Randomised Controlled Trial
Participants
View on DOI

Cite this study

Li, S., Rong, P., Wang, Y., Jin, G., Hou, X., Li, S., Xiao, X., Zhou, W., Wu, Y., Liu, Y., Zhang, Y., Zhao, B., Huang, Y., Cao, J., Chen, H., Hodges, S., Vangel, M., & Kong, J. (2022). Comparative Effectiveness of Transcutaneous Auricular Vagus Nerve Stimulation vs Citalopram for Major Depressive Disorder: A Randomized Trial. Neuromodulation: Technology at the Neural Interface, 25(3), 450-460. https://doi.org/10.1016/j.neurom.2021.10.021

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