Protocol of the randomized double blind sham controlled AddVNS study of transcutaneous vagus nerve stimulation mechanisms in depression
Kokolakis E, von Mücke-Heim IA, Pape JC, Grandi NC, Erhardt A, Sämann PG, Spoormaker V, Gogolla N, Binder EB, Falkai P
Scientific Reports · 2026
Key finding
We believe it to significantly advance our mechanistic understanding and subsequently clinical translation of this promising intervention.
- Condition
- Depression
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
Cite this study
Kokolakis, E., von Mücke-Heim, I. A., Pape, J. C., Grandi, N. C., Erhardt, A., Sämann, P. G., Spoormaker, V., Gogolla, N., Binder, E. B., & Falkai, P. (2026). Protocol of the randomized double blind sham controlled AddVNS study of transcutaneous vagus nerve stimulation mechanisms in depression. Scientific Reports, 16(1). https://doi.org/10.1038/s41598-026-42459-2
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Summary by Vagus Research. Always consult the primary source for the authoritative record.