A 5-year observational study of patients with treatment-resistant depression treated with vagus nerve stimulation or treatment as usual: comparison of response, remission, and suicidality
Aaronson ST, Sears P, Ruvuna F, Bunker M, Conway CR, Dougherty DD, Reimherr FW, Schwartz TL, Zajecka JM
American Journal of Psychiatry · 2017
Key finding
Over 5 years, VNS plus treatment as usual produced significantly higher cumulative response rates (67.6% vs 40.9%) and remission rates (43.3% vs 25.7%) compared to treatment as usual alone in treatment-resistant depression.
- Condition
- Depression
- Stimulation
- iVNS
- Evidence tier
- Observational / Cohort
- Participants
- 795
Cite this study
Aaronson, S. T., Sears, P., Ruvuna, F., Bunker, M., Conway, C. R., Dougherty, D. D., Reimherr, F. W., Schwartz, T. L., & Zajecka, J. M. (2017). A 5-year observational study of patients with treatment-resistant depression treated with vagus nerve stimulation or treatment as usual: comparison of response, remission, and suicidality. American Journal of Psychiatry, 174(7), 640-648. https://doi.org/10.1176/appi.ajp.2017.16010034
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Summary by Vagus Research. Always consult the primary source for the authoritative record.