Noninvasive vagus nerve stimulation as acute therapy for migraine: the randomized PRESTO study
Tassorelli C, Grazzi L, de Tommaso M, Pierangeli G, Martelletti P, Rainero I, Dorlas S, Geppetti P, Ambrosini A, Sarchielli P, et al.
Neurology · 2018
Key finding
Non-invasive cervical VNS was safe and well-tolerated for acute migraine treatment, though the primary endpoint of pain-free status at 2 hours did not reach significance versus sham.
- Condition
- Migraine
- Stimulation
- tcVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 248
Cite this study
Tassorelli, C., Grazzi, L., de Tommaso, M., Pierangeli, G., Martelletti, P., Rainero, I., Dorlas, S., Geppetti, P., Ambrosini, A., Sarchielli, P., Liebler, E., Barbanti, P., Tassorelli, C., Bitetto, V., De Icco, R., Martinelli, D., Sances, G., Bianchi, M., Grazzi, L., … Di Maro, D. (2018). Noninvasive vagus nerve stimulation as acute therapy for migraine: the randomized PRESTO study. Neurology, 91(4). https://doi.org/10.1212/WNL.0000000000005857
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Summary by Vagus Research. Always consult the primary source for the authoritative record.