Noninvasive vagus nerve stimulation for migraine: a systematic review and meta-analysis of randomized controlled trials
Song D, Li P, Wang Y, Cao J
Frontiers in Neurology · 2023
Key finding
Meta-analysis shows that non-invasive cervical vagus nerve stimulation (n-cVNS) significantly impacted ≥50% responder rate (OR, 1.64; 95% CI, 1.1 to 2.47; p = 0.02), but had no significant effect on reducing migraine days (MD, -0.46; 95% CI, -1.21 to 0.29; p = 0.23) and headache days (MD, -0.68; ...
- Condition
- Migraine
- Stimulation
- iVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
Cite this study
Song, D., Li, P., Wang, Y., & Cao, J. (2023). Noninvasive vagus nerve stimulation for migraine: a systematic review and meta-analysis of randomized controlled trials. Frontiers in Neurology, 14. https://doi.org/10.3389/fneur.2023.1190062
Related studies in Migraine
Effectiveness of non-invasive vagus nerve stimulation vs heart rate variability biofeedback interventions for chronic pain conditions: A systematic review
Pellow et al. · Scandinavian journal of pain · 2025 · Systematic Review / Meta-Analysis
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Duff et al. · Pain and therapy · 2024 · Systematic Review / Meta-Analysis
[Clinical efficacy of auricular vagus nerve stimulation in the treatment of chronic and acute pain : A systematic review]
Likar et al. · Schmerz (Berlin, Germany) · 2024 · Systematic Review / Meta-Analysis
Transcutaneous vagus nerve stimulation effects on chronic pain: systematic review and meta-analysis
Costa et al. · Pain reports · 2024 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.