Chronic migraine headache prevention with noninvasive vagus nerve stimulation: The EVENT study
Silberstein SD, Calhoun AH, Lipton RB, Grosberg BM, Cady RK, Dorlas S, Simmons KA, Mullin C, Liebler EJ, Goadsby PJ, et al.
Neurology · 2016
Key finding
First sham-controlled pilot study of nVNS for chronic migraine prevention; open-label completers showed approximately 7.9 fewer headache days after 8 months of sustained therapy.
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- Condition
- Migraine
- Stimulation
- tcVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 59
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Cite this study
Silberstein, S. D., Calhoun, A. H., Lipton, R. B., Grosberg, B. M., Cady, R. K., Dorlas, S., Simmons, K. A., Mullin, C., Liebler, E. J., Goadsby, P. J., Saper, J. R., Calhoun, A. H., Cady, R. K., Dexter, J., Silberstein, S. D., Young, W., Marmura, M., Nahas-Geiger, S., Da Silva, A., … Eller, M. (2016). Chronic migraine headache prevention with noninvasive vagus nerve stimulation: The EVENT study. Neurology, 87(5), 529-538. https://doi.org/10.1212/WNL.0000000000002918
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