Vagal Neuromodulation in Chronic Heart Failure With Reduced Ejection Fraction: A Systematic Review and Meta-Analysis
Sant'Anna LB, Couceiro SLM, Ferreira EA, Sant'Anna MB, Cardoso PR, Mesquita ET, Sant'Anna GM, Sant'Anna FM
Frontiers in Cardiovascular Medicine · 2021
Key finding
Pooled analysis of randomized vagus nerve stimulation trials in HFrEF showed improvements in NYHA class, quality of life, and 6-minute walk distance but no significant effect on mortality or left ventricular remodelling.
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- Condition
- Heart Failure
- Stimulation
- iVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
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Cite this study
Sant'Anna, L. B., Couceiro, S. L. M., Ferreira, E. A., Sant'Anna, M. B., Cardoso, P. R., Mesquita, E. T., Sant'Anna, G. M., & Sant'Anna, F. M. (2021). Vagal Neuromodulation in Chronic Heart Failure With Reduced Ejection Fraction: A Systematic Review and Meta-Analysis. Frontiers in Cardiovascular Medicine, 8. https://doi.org/10.3389/fcvm.2021.766676
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