Non-invasive neurostimulation for drug-resistant epilepsy: systematic review and meta-analysis of effectiveness, safety, and optimal stimulation parameters
Premaratne S, Zoghi M, Antonic-Baker A, Chen Z, Chen L, Hamer R, Major B, Thomas EHX, Kwan P, O’Brien TJ, et al.
Journal of Neurology · 2025
Key finding
These findings, while encouraging, should be interpreted in the context of methodological heterogeneity between studies and overall low certainty of evidence.
- Condition
- Safety
- Stimulation
- tcVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
Cite this study
Premaratne, S., Zoghi, M., Antonic-Baker, A., Chen, Z., Chen, L., Hamer, R., Major, B., Thomas, E. H. X., Kwan, P., O’Brien, T. J., Lundstrom, B. N., & Simpson, H. D. (2025). Non-invasive neurostimulation for drug-resistant epilepsy: systematic review and meta-analysis of effectiveness, safety, and optimal stimulation parameters. Journal of Neurology, 273(1). https://doi.org/10.1007/s00415-025-13522-1
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