Controlled Clinical TrialiVNSn = 235

Vagus nerve stimulation: 2-year outcomes for bipolar versus unipolar treatment-resistant depression

Nierenberg AA, Alpert JE, Gardner-Schuster EE, Seay S, Mischoulon D

Biological Psychiatry · 2008

Key finding

Acute, 1-year and 2-year VNS outcomes were similar for the 25 bipolar and the unipolar treatment-resistant depression patients.

Condition
Bipolar Disorder
Stimulation
iVNS
Evidence tier
Controlled Clinical Trial
Participants
235
View on DOI

Cite this study

Nierenberg, A. A., Alpert, J. E., Gardner-Schuster, E. E., Seay, S., & Mischoulon, D. (2008). Vagus nerve stimulation: 2-year outcomes for bipolar versus unipolar treatment-resistant depression. Biological Psychiatry, 64(6), 455-460. https://doi.org/10.1016/j.biopsych.2008.04.036

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