Controlled Clinical TrialiVNSn = 9

A 1-year pilot study of vagus nerve stimulation in treatment-resistant rapid-cycling bipolar disorder

Marangell LB, Suppes T, Zboyan HA, Prashad SJ, Fischer G, Snow D, Sureddi S, Allen JC

The Journal of Clinical Psychiatry · 2008

Key finding

Open-label adjunctive VNS over 12 months produced a 38.1% mean improvement in overall illness and was well tolerated in treatment-resistant rapid-cycling bipolar disorder.

Condition
Bipolar Disorder
Stimulation
iVNS
Evidence tier
Controlled Clinical Trial
Participants
9
View on DOI

Cite this study

Marangell, L. B., Suppes, T., Zboyan, H. A., Prashad, S. J., Fischer, G., Snow, D., Sureddi, S., & Allen, J. C. (2008). A 1-year pilot study of vagus nerve stimulation in treatment-resistant rapid-cycling bipolar disorder. The Journal of Clinical Psychiatry, 69(2), 183-189. https://doi.org/10.4088/jcp.v69n0203

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