Possible Glycemic Effects of Vagus Nerve Stimulation Evaluated by Continuous Glucose Monitoring in People with Diabetes and Autonomic Neuropathy: A Randomized, Sham-Controlled Trial
Kufaishi H, Bertoli D, Kornum DS, Ranjan AG, Nørgaard K, Krogh K, Brock B, Okdahl T, Frøkjær JB, Drewes AM, et al.
Diabetes Technology & Therapeutics · 2025
Key finding
For the 8-week treatment period, changes in CV and TIR between groups were also nonsignificant.
- Condition
- Metabolic
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 145
Cite this study
Kufaishi, H., Bertoli, D., Kornum, D. S., Ranjan, A. G., Nørgaard, K., Krogh, K., Brock, B., Okdahl, T., Frøkjær, J. B., Drewes, A. M., Brock, C., Krag Knop, F., Hansen, T. W., Hansen, C. S., & Rossing, P. (2025). Possible Glycemic Effects of Vagus Nerve Stimulation Evaluated by Continuous Glucose Monitoring in People with Diabetes and Autonomic Neuropathy: A Randomized, Sham-Controlled Trial. Diabetes Technology & Therapeutics, 27(1), 52-59. https://doi.org/10.1089/dia.2024.0175
Related studies in Metabolic
Brain-gut interaction for holistic regulation: Transcutaneous auricular vagus nerve stimulation in modulating glucose and lipid metabolic disorders
Zou et al. · Clinical nutrition (Edinburgh, Scotland) · 2026 · Controlled Clinical Trial
Combining Celiac and Hepatic Vagus Nerve Neuromodulation Reverses Glucose Intolerance and Improves Glycemic Control in Pre- and Overt-Type 2 Diabetes Mellitus
Waataja et al. · Biomedicines · 2023 · Controlled Clinical Trial
Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism
Borgmann et al. · Cell metabolism · 2021 · Controlled Clinical Trial
Pancreatic β-Cells Communicate With Vagal Sensory Neurons
Makhmutova et al. · Gastroenterology · 2021 · Controlled Clinical Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.