Vagus nerve stimulation for primary headache disorders: An anatomical review to explain a clinical phenomenon
Henssen DJHA, Derks B, van Doorn M, Verhoogt N, Van Cappellen van Walsum AM, Staats P, Vissers K
Cephalalgia · 2019
Key finding
The first part of this review shows that nVNS in primary headache disorders is moderately effective, safe and well-tolerated.
Auto-extracted · verification pendingHow we verify
- Condition
- Safety
- Stimulation
- iVNS
- Evidence tier
- Narrative / Scoping Review
- Participants
- —
Share this study
Download the citation card as a PNG, or copy a link to this page.
Cite this study
Henssen, D. J. H. A., Derks, B., van Doorn, M., Verhoogt, N., Van Cappellen van Walsum, A. M., Staats, P., & Vissers, K. (2019). Vagus nerve stimulation for primary headache disorders: An anatomical review to explain a clinical phenomenon. Cephalalgia, 39(9), 1180-1194. https://doi.org/10.1177/0333102419833076
Related studies in Safety
The role of transcutaneous auricular vagus nerve stimulation in chronic pain: from neurobiological mechanisms to clinical applications
Zhang et al. · Frontiers in pain research (Lausanne, Switzerland) · 2026 · Systematic Review / Meta-Analysis
Systematic review for VNS vs. pharmaceutical modulations for multifaceted neurological disorder management through cross-case, network meta-analysis
Han et al. · Brain stimulation · 2025 · Systematic Review / Meta-Analysis
Efficacy of transcutaneous vagus nerve stimulation (t-VNS) in treating drug-resistant epilepsy: A systematic review and meta-analysis
Makkawi et al. · Epilepsy research · 2025 · Systematic Review / Meta-Analysis
Optimizing vagus nerve stimulation for Super Refractory Status Epilepticus: A case series and systematic review
Pichardo-Rojas et al. · Epileptic disorders : international epilepsy journal with videotape · 2025 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.