Transcutaneous Auricular Vagus Nerve Stimulation and Pectoral-Intercostal Fascial Block for the Prevention of Chronic Postsurgical Pain in Elderly Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A 2x2 Factorial, Double-Blinded, Randomized Clinical Trial
Cui S, Yan L, Huang P, Yang H, Liang W, Huang L
Clinical Interventions in Aging · 2026
Key finding
Perioperative taVNS significantly reduced chronic postsurgical pain incidence (28.6% vs 40.9%) and improved recovery quality after off-pump CABG.
Auto-extracted · verification pendingHow we verify
- Condition
- Pain
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 260
Share this study
Download the citation card as a PNG, or copy a link to this page.
Cite this study
Cui, S., Yan, L., Huang, P., Yang, H., Liang, W., & Huang, L. (2026). Transcutaneous Auricular Vagus Nerve Stimulation and Pectoral-Intercostal Fascial Block for the Prevention of Chronic Postsurgical Pain in Elderly Patients Undergoing Off-Pump Coronary Artery Bypass Grafting: A 2x2 Factorial, Double-Blinded, Randomized Clinical Trial. Clinical Interventions in Aging, Volume 21, 1-15. https://doi.org/10.2147/cia.s583971
Related studies in Pain
The Effect of Vagus Nerve Stimulation on Pain Severity Scores in Patients With Chronic Musculoskeletal Pain Syndrome: A Meta-Analysis
Buchman et al. · Cureus · 2026 · Systematic Review / Meta-Analysis
Effectiveness of non-invasive vagus nerve stimulation vs heart rate variability biofeedback interventions for chronic pain conditions: A systematic review
Pellow et al. · Scandinavian journal of pain · 2025 · Systematic Review / Meta-Analysis
Clinical Efficacy of Auricular Vagus Nerve Stimulation in the Treatment of Chronic and Acute Pain: A Systematic Review and Meta-analysis
Duff et al. · Pain and therapy · 2024 · Systematic Review / Meta-Analysis
[Clinical efficacy of auricular vagus nerve stimulation in the treatment of chronic and acute pain : A systematic review]
Likar et al. · Schmerz (Berlin, Germany) · 2024 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.