The Effect of Vagus Nerve Stimulation on Pain Severity Scores in Patients With Chronic Musculoskeletal Pain Syndrome: A Meta-Analysis
Buchman ZJ, Lorea JC, Oar DP, DiSilvestro D, Jay LF, Lazo CR, Clark M
Cureus · 2026
Key finding
Meta-analysis of six trials found tVNS reduced chronic musculoskeletal pain scores by an amount exceeding the minimal clinically important difference.
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- Condition
- Pain
- Stimulation
- taVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
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Cite this study
Buchman, Z. J., Lorea, J. C., Oar, D. P., DiSilvestro, D., Jay, L. F., Lazo, C. R., & Clark, M. (2026). The Effect of Vagus Nerve Stimulation on Pain Severity Scores in Patients With Chronic Musculoskeletal Pain Syndrome: A Meta-Analysis. Cureus. https://doi.org/10.7759/cureus.103313
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