The vagus nerve at the interface of the microbiota-gut-brain axis
Bonaz B, Bazin T, Pellissier S
Frontiers in Neuroscience · 2018
Key finding
Review establishing the vagus nerve as a key communication pathway between gut microbes and the brain, with vagal afferents sensing microbial metabolites and the cholinergic anti-inflammatory pathway modulating intestinal inflammation.
- Condition
- Gut Health
- Stimulation
- iVNS
- Evidence tier
- Narrative / Scoping Review
- Participants
- —
Cite this study
Bonaz, B., Bazin, T., & Pellissier, S. (2018). The vagus nerve at the interface of the microbiota-gut-brain axis. Frontiers in Neuroscience, 12. https://doi.org/10.3389/fnins.2018.00049
Related studies in Gut Health
Vagal Nerve Stimulation for Chronic Constipation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Saleh et al. · Neuromodulation : journal of the International Neuromodulation Society · 2026 · Systematic Review / Meta-Analysis
Efficacy of vagus nerve stimulation in gastrointestinal disorders: a systematic review
Veldman et al. · Gastroenterology report · 2025 · Systematic Review / Meta-Analysis
Vagus nerve stimulation in autoimmune conditions: a systematic review
Lombo et al. · ACR Open Rheumatology · 2025 · Systematic Review / Meta-Analysis
Assessing the therapeutic potential of vagus nerve stimulation in autoimmune diseases: A systematic review
Chan et al. · Physiological reports · 2025 · Systematic Review / Meta-Analysis
Summary by Vagus Research. Always consult the primary source for the authoritative record.