Home-based transcutaneous auricular vagus nerve stimulation (taVNS) improves motor and non-motor symptoms by improving autonomic and brain functions in patients with Parkinson's disease: A randomized clinical trial
Wang R, Liu M, Liu Q, You Y, Li X, Chen Y, Liu Y, Wang J, Wang M, Wang X, et al.
Neurotherapeutics · 2026
Key finding
Three weeks of home-based taVNS significantly reduced MDS-UPDRS III motor scores versus sham, accompanied by decreased striatal and thalamic glutamate and elevated serum acetylcholine.
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- Condition
- Parkinson's Disease
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 41
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Cite this study
Wang, R., Liu, M., Liu, Q., You, Y., Li, X., Chen, Y., Liu, Y., Wang, J., Wang, M., Wang, X., Yin, Z., Chen, J. D., Li, X., & Wang, H. (2026). Home-based transcutaneous auricular vagus nerve stimulation (taVNS) improves motor and non-motor symptoms by improving autonomic and brain functions in patients with Parkinson's disease: A randomized clinical trial. Neurotherapeutics, 23(1), e00832. https://doi.org/10.1016/j.neurot.2026.e00832
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