Auricular vagus nerve stimulation reduces postoperative delirium after major non-cardiac surgery: a randomized controlled trial
Shi J, Gao D, Hu X, Zhang Y, Guo T, Mao Q, Liu Q, Ji M
Clinical Interventions in Aging · 2026
Key finding
Sham-controlled RCT in older patients found taVNS reduced postoperative delirium (12% vs 25.3%), partly mediated by improved postoperative sleep.
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- Condition
- Postoperative Recovery
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 150
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Cite this study
Shi, J., Gao, D., Hu, X., Zhang, Y., Guo, T., Mao, Q., Liu, Q., & Ji, M. (2026). Auricular vagus nerve stimulation reduces postoperative delirium after major non-cardiac surgery: a randomized controlled trial. Clinical Interventions in Aging, Volume 21, 1-12. https://doi.org/10.2147/CIA.S558395
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