The EMPOWER study: randomized, prospective, double-blind, multicenter trial of vagal blockade to induce weight loss in morbid obesity
Sarr MG, Billington CJ, Brancatisano R, Brancatisano A, Toouli J, Kow L, Nguyen NT, Blackstone R, Maher JW, Shikora S, et al.
Obesity Surgery · 2012
Key finding
In 294 implanted morbidly obese patients, vagal blockade produced 17% excess weight loss at 12 months but did not significantly exceed the control group, which experienced an unexpectedly large response from low-level device current.
- Condition
- Obesity
- Stimulation
- iVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 294
Cite this study
Sarr, M. G., Billington, C. J., Brancatisano, R., Brancatisano, A., Toouli, J., Kow, L., Nguyen, N. T., Blackstone, R., Maher, J. W., Shikora, S., Reeds, D. N., Eagon, J. C., Wolfe, B. M., O’Rourke, R. W., Fujioka, K., Takata, M., Swain, J. M., Morton, J. M., Ikramuddin, S., … Rosenthal, R. (2012). The EMPOWER study: randomized, prospective, double-blind, multicenter trial of vagal blockade to induce weight loss in morbid obesity. Obesity Surgery, 22(11), 1771-1782. https://doi.org/10.1007/s11695-012-0751-8
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Summary by Vagus Research. Always consult the primary source for the authoritative record.