The long-term effect of vagus nerve stimulation on quality of life in patients with pharmacoresistant focal epilepsy: the PuLsE trial
Ryvlin P, Gilliam FG, Nguyen DK, Colicchio G, Iudice A, Tinuper P, Zamponi N, Aguglia U, Wagner L, Minotti L, et al.
Epilepsia · 2014
Key finding
VNS plus best medical practice improved health-related quality of life and reduced seizures versus best medical practice alone over 12 months.
- Condition
- Epilepsy
- Stimulation
- iVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 112
Cite this study
Ryvlin, P., Gilliam, F. G., Nguyen, D. K., Colicchio, G., Iudice, A., Tinuper, P., Zamponi, N., Aguglia, U., Wagner, L., Minotti, L., Stefan, H., Boon, P., Sadler, M., Benna, P., Raman, P., & Perucca, E. (2014). The long-term effect of vagus nerve stimulation on quality of life in patients with pharmacoresistant focal epilepsy: the PuLsE trial. Epilepsia, 55(6), 893-900. https://doi.org/10.1111/epi.12611
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Summary by Vagus Research. Always consult the primary source for the authoritative record.