Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study
Peterson D, Van Poppel M, Boling W, Santos P, Schwalb J, Eisenberg H, Mehta A, Spader H, Botros J, Vrionis FD, et al.
Bioelectronic Medicine · 2024
Key finding
Sixty patients were implanted during Stage 1 of the study.
- Condition
- Rheumatoid Arthritis
- Stimulation
- iVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
Cite this study
Peterson, D., Van Poppel, M., Boling, W., Santos, P., Schwalb, J., Eisenberg, H., Mehta, A., Spader, H., Botros, J., Vrionis, F. D., Ko, A., Adelson, P. D., Lega, B., Konrad, P., Calle, G., Vale, F. L., Bucholz, R., & Richardson, R. M. (2024). Clinical safety and feasibility of a novel implantable neuroimmune modulation device for the treatment of rheumatoid arthritis: initial results from the randomized, double-blind, sham-controlled RESET-RA study. Bioelectronic Medicine, 10(1). https://doi.org/10.1186/s42234-023-00138-x
Related studies in Rheumatoid Arthritis
Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial
Tesser et al. · Nature medicine · 2026 · Randomised Controlled Trial
A randomized, double-blind, sham-controlled, clinical trial of auricular vagus nerve stimulation for the treatment of active rheumatoid arthritis: comment on the article by Baker et al
Aranow et al. · Arthritis & rheumatology (Hoboken, N.J.) · 2025 · Randomised Controlled Trial
A Randomized, Double-Blind, Sham-Controlled, Clinical Trial of Auricular Vagus Nerve Stimulation for the Treatment of Active Rheumatoid Arthritis
Baker et al. · Arthritis & rheumatology (Hoboken, N.J.) · 2023 · Randomised Controlled Trial
Home-based respiratory-gated transcutaneous auricular vagus nerve stimulation for rheumatoid arthritis—a feasibility study
Parikh et al. · Clinical Rheumatology · 2026 · Controlled Clinical Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.