Observational / CohortiVNSn = 22

Fast cycle of vagus nerve stimulation is associated with increased sleep-related breathing disorder in patients with epilepsy

Massa J, El Youssef N, Carron R, Garcia P, Trebuchon A, Giusiano B, Bartolomei F, Marchi A, Lambert I

Epilepsia · 2026

Key finding

Among 22 epilepsy patients, a fast VNS cycle (shorter interval between stimulations) was independently associated with a higher apnea-hypopnea index on polysomnography.

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Condition
Epilepsy
Stimulation
iVNS
Evidence tier
Observational / Cohort
Participants
22
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Cite this study

Massa, J., El Youssef, N., Carron, R., Garcia, P., Trebuchon, A., Giusiano, B., Bartolomei, F., Marchi, A., & Lambert, I. (2026). Fast cycle of vagus nerve stimulation is associated with increased sleep-related breathing disorder in patients with epilepsy. Epilepsia, 67(5), 2347-2357. https://doi.org/10.1002/epi.70147

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