Randomised Controlled TrialtaVNS

The effects of transcutaneous auricular vagus nerve stimulation in epilepsy comorbid with migraine on the EEG power spectrum: a randomized controlled trial

Ma S, Du J, Luo C, Wu X, Liu L, Liu T, Zhang X, Yang L, Liu J, Luo Y, et al.

Frontiers in Neurology · 2025

Key finding

The frequencies of migraine attacks and seizures significantly decreased in the taVNS group from baseline to 24 weeks (migraine attack frequency, p = 0.002; seizure frequency, p = 0.004), and so did in Self-Rating Anxiety Scale (SAS) score (p < 0.001) and Self-Rating Depression Scale (SDS) score ...

Condition
Migraine
Stimulation
taVNS
Evidence tier
Randomised Controlled Trial
Participants
View on DOI

Cite this study

Ma, S., Du, J., Luo, C., Wu, X., Liu, L., Liu, T., Zhang, X., Yang, L., Liu, J., Luo, Y., Zhang, S., Rodriguez-Labrada, R., & Zhu, Q. (2025). The effects of transcutaneous auricular vagus nerve stimulation in epilepsy comorbid with migraine on the EEG power spectrum: a randomized controlled trial. Frontiers in Neurology, 16. https://doi.org/10.3389/fneur.2025.1694455

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