Observational / CohortiVNS

Long-term outcome and predictors of vagus nerve stimulation for drug-resistant epilepsy: Real-world evidence from the Korean national hospital consortium

Lee SY, Lee H, Cho JW, Kang KW, Seo JG, Kim JS, Kang JW, Kim D, Kim YS, Choi SA, et al.

Epilepsy Research · 2025

Key finding

The seizure frequency exhibited a decreasing trend in 27.5 % and an increasing trend in 3.8 % during the first year following VNS implantation without a significant change in efficacy over the subsequent three years.

Condition
Epilepsy
Stimulation
iVNS
Evidence tier
Observational / Cohort
Participants
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Cite this study

Lee, S. Y., Lee, H., Cho, J. W., Kang, K. W., Seo, J. G., Kim, J. S., Kang, J. W., Kim, D., Kim, Y. S., Choi, S. A., Park, J., Phi, J. H., Nam, S. O., Kim, W. S., Kim, J. M., & Kim, K. J. (2025). Long-term outcome and predictors of vagus nerve stimulation for drug-resistant epilepsy: Real-world evidence from the Korean national hospital consortium. Epilepsy Research, 210, 107511. https://doi.org/10.1016/j.eplepsyres.2025.107511

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