Vagus Nerve Stimulation and Seizure Outcomes in Pediatric Refractory Epilepsy: Systematic Review and Meta-analysis
Jain P, Arya R
Neurology · 2021
Key finding
A systematic review of 101 studies of VNS in paediatric refractory epilepsy found a pooled 50%-responder rate of 56% and seizure freedom of 12% at ~2.5 years; fewer prior medications and later seizure onset predicted better outcomes.
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- Condition
- Epilepsy
- Stimulation
- iVNS
- Evidence tier
- Systematic Review / Meta-Analysis
- Participants
- —
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Cite this study
Jain, P., & Arya, R. (2021). Vagus Nerve Stimulation and Seizure Outcomes in Pediatric Refractory Epilepsy: Systematic Review and Meta-analysis. Neurology, 96(22), 1041-1051. https://doi.org/10.1212/WNL.0000000000012030
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