Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes
Inoue T, Abe C, Sung SSJ, Moscalu S, Jankowski J, Huang L, Ye H, Rosin DL, Guyenet PG, Okusa MD
Journal of Clinical Investigation · 2016
Key finding
Together, these results demonstrate that VNS-mediated attenuation of AKI and systemic inflammation depends on α7nAChR-positive splenocytes.
- Condition
- Rheumatoid Arthritis
- Stimulation
- iVNS
- Evidence tier
- Controlled Clinical Trial
- Participants
- —
Cite this study
Inoue, T., Abe, C., Sung, S. S. J., Moscalu, S., Jankowski, J., Huang, L., Ye, H., Rosin, D. L., Guyenet, P. G., & Okusa, M. D. (2016). Vagus nerve stimulation mediates protection from kidney ischemia-reperfusion injury through α7nAChR+ splenocytes. Journal of Clinical Investigation, 126(5), 1939-1952. https://doi.org/10.1172/JCI83658
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Summary by Vagus Research. Always consult the primary source for the authoritative record.