Effect of non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) on non-motor symptoms in multiple sclerosis: study protocol for a randomised, controlled trial
Herr T, Gamain J, Strauss S, Szeska C, Flöel A, Penner IK, Weymar M, Grothe M
BMJ Open · 2025
Key finding
Transcutaneous auricular vagus nerve stimulation (taVNS) has been found to be a cognitive enhancer in preclinical research and was successfully used for the treatment of psychiatric and neurological disorders to combat dysfunctional cognitive and affective processes.
- Condition
- Multiple Sclerosis
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
Cite this study
Herr, T., Gamain, J., Strauss, S., Szeska, C., Flöel, A., Penner, I. K., Weymar, M., & Grothe, M. (2025). Effect of non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) on non-motor symptoms in multiple sclerosis: study protocol for a randomised, controlled trial. BMJ Open, 15(11), e103998. https://doi.org/10.1136/bmjopen-2025-103998
Related studies in Multiple Sclerosis
The Vagus Nerve Somatosensory-evoked Potential in Neural Disorders: Systematic Review and Illustrative Vignettes
Leon-Ariza et al. · Clinical EEG and neuroscience · 2022 · Systematic Review / Meta-Analysis
Effect of non-invasive transcutaneous auricular vagus nerve stimulation on cerebral motor excitability-Study protocol for a randomized, sham controlled trial
Herr et al. · Frontiers in neurology · 2023 · Randomised Controlled Trial
Vagus nerve stimulation enhances remyelination and decreases innate neuroinflammation in lysolecithin-induced demyelination
Bachmann et al. · Brain stimulation · 2024 · Controlled Clinical Trial
Paired vagus nerve stimulation drives precise remyelination and motor recovery after myelin loss
Huang et al. · bioRxiv : the preprint server for biology · 2024 · Controlled Clinical Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.