Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham controlled trial
Gurel NZ, Wittbrodt MT, Jung H, Shandhi MMH, Driggers EG, Ladd SL, Huang M, Ko YA, Shallenberger L, Beckwith J, et al.
Neurobiology of Stress · 2020
Key finding
tcVNS attenuated sympathetic arousal during traumatic and mental stress in PTSD patients, decreasing heart rate and increasing peripheral vasodilation compared to sham over a three-day protocol.
- Condition
- PTSD
- Stimulation
- tcVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 25
Cite this study
Gurel, N. Z., Wittbrodt, M. T., Jung, H., Shandhi, M. M. H., Driggers, E. G., Ladd, S. L., Huang, M., Ko, Y. A., Shallenberger, L., Beckwith, J., Nye, J. A., Pearce, B. D., Vaccarino, V., Shah, A. J., Inan, O. T., & Bremner, J. D. (2020). Transcutaneous cervical vagal nerve stimulation reduces sympathetic responses to stress in posttraumatic stress disorder: A double-blind, randomized, sham controlled trial. Neurobiology of Stress, 13, 100264. https://doi.org/10.1016/j.ynstr.2020.100264
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Summary by Vagus Research. Always consult the primary source for the authoritative record.