Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A randomized, double-blind, sham-controlled ACT2 study
Goadsby PJ, de Coo IF, Silver N, Tyagi A, Ahmed F, Gaul C, Jensen RH, Diener HC, Solbach K, Straube A, et al.
Cephalalgia · 2018
Key finding
nVNS achieved pain-free status in 48% of episodic cluster headache attacks versus 6% with sham, confirming efficacy of gammaCore for episodic cluster headache.
- Condition
- Cluster Headache
- Stimulation
- tcVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 92
Cite this study
Goadsby, P. J., de Coo, I. F., Silver, N., Tyagi, A., Ahmed, F., Gaul, C., Jensen, R. H., Diener, H. C., Solbach, K., Straube, A., Liebler, E., Marin, J. C., & Ferrari, M. D. (2018). Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A randomized, double-blind, sham-controlled ACT2 study. Cephalalgia, 38(5), 959-969. https://doi.org/10.1177/0333102417744362
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Summary by Vagus Research. Always consult the primary source for the authoritative record.