Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A randomized, double-blind, sham-controlled ACT2 study
Goadsby PJ, de Coo IF, Silver N, Tyagi A, Ahmed F, Gaul C, Jensen RH, Diener HC, Solbach K, Straube A, et al.
Cephalalgia · 2018
Key finding
In the ACT2 RCT, non-invasive cervical VNS achieved pain-free acute cluster-headache attacks more often than sham.
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- Condition
- Cluster Headache
- Stimulation
- tcVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 92
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Cite this study
Goadsby, P. J., de Coo, I. F., Silver, N., Tyagi, A., Ahmed, F., Gaul, C., Jensen, R. H., Diener, H. C., Solbach, K., Straube, A., Liebler, E., Marin, J. C., & Ferrari, M. D. (2018). Non-invasive vagus nerve stimulation for the acute treatment of episodic and chronic cluster headache: A randomized, double-blind, sham-controlled ACT2 study. Cephalalgia, 38(5), 959-969. https://doi.org/10.1177/0333102417744362
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Summary by Vagus Research. Always consult the primary source for the authoritative record.