Transcutaneous auricular vagus nerve stimulation modifies cortical excitability in middle-aged and older adults
Gerges ANH, Graetz L, Hillier S, Uy J, Hamilton T, Opie G, Vallence A, Braithwaite FA, Chamberlain S, Hordacre B
Psychophysiology · 2025
Key finding
In a double-blind randomised crossover sham-controlled study of healthy middle-aged and older adults, taVNS increased short-interval intracortical inhibition in M1, demonstrating that taVNS modulates cortical excitability in an ageing population.
- Condition
- Neuroplasticity
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- 23
Cite this study
Gerges, A. N. H., Graetz, L., Hillier, S., Uy, J., Hamilton, T., Opie, G., Vallence, A., Braithwaite, F. A., Chamberlain, S., & Hordacre, B. (2025). Transcutaneous auricular vagus nerve stimulation modifies cortical excitability in middle-aged and older adults. Psychophysiology, 62(1). https://doi.org/10.1111/psyp.14584
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Summary by Vagus Research. Always consult the primary source for the authoritative record.