Transcutaneous auricular vagus nerve stimulation modulates masseter muscle activity, pain perception, and anxiety levels in university students: a double-blind, randomized, controlled clinical trial
Ferreira LMA, Brites R, Fraião G, Pereira G, Fernandes H, de Brito JAA, Pereira Generoso L, Maziero Capello MG, Pereira GS, Scoz RD, et al.
Frontiers in Integrative Neuroscience · 2024
Key finding
Active TAVNS significantly reduced both left and right masseter activation during resting mandibular position, persisting for 2 weeks post-intervention.
- Condition
- Anxiety
- Stimulation
- taVNS
- Evidence tier
- Randomised Controlled Trial
- Participants
- —
Cite this study
Ferreira, L. M. A., Brites, R., Fraião, G., Pereira, G., Fernandes, H., de Brito, J. A. A., Pereira Generoso, L., Maziero Capello, M. G., Pereira, G. S., Scoz, R. D., Silva, J. R. T., & Silva, M. L. (2024). Transcutaneous auricular vagus nerve stimulation modulates masseter muscle activity, pain perception, and anxiety levels in university students: a double-blind, randomized, controlled clinical trial. Frontiers in Integrative Neuroscience, 18. https://doi.org/10.3389/fnint.2024.1422312
Related studies in Anxiety
Transcutaneous auricular vagus nerve stimulation for functional dyspepsia: A systematic review and meta-analysis
Lee et al. · Complementary therapies in medicine · 2025 · Systematic Review / Meta-Analysis
Efficacy and Safety of Electroacupuncture Through Nerve Stimulation in Patients With Anxiety Disorders: Protocol for a Randomized, Assessor-Blind, Three-Arm, Parallel-Group Clinical Trial
Jung et al. · JMIR research protocols · 2025 · Randomised Controlled Trial
Evaluating PEMF vagus nerve stimulation through neck application: A randomized placebo study with volunteers
Jerman et al. · Electromagnetic biology and medicine · 2025 · Randomised Controlled Trial
Transcutaneous auricular vagus nerve stimulation to treat narcolepsy type 1 (TARGET-NT1): A two-arm, randomised, sham-controlled trial
Pan et al. · Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025 · Randomised Controlled Trial
Summary by Vagus Research. Always consult the primary source for the authoritative record.