Observational / CohortiVNSn = 195

Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures (E04)

DeGiorgio C, Schachter S, Handforth A, Salinsky M, Thompson J, Uthman B, Reed R, Collins S, Tecoma E, Morris G, et al.

Epilepsia · 2000

Key finding

Median seizure reduction reached roughly 45% at 12 months, with efficacy increasing over the first year of VNS therapy.

Auto-extracted · verification pendingHow we verify

Condition
Epilepsy
Stimulation
iVNS
Evidence tier
Observational / Cohort
Participants
195
View on PubMed

Share this study

Download the citation card as a PNG, or copy a link to this page.

Cite this study

DeGiorgio, C., Schachter, S., Handforth, A., Salinsky, M., Thompson, J., Uthman, B., Reed, R., Collins, S., Tecoma, E., Morris, G., Vaughn, B., Naritoku, D., Henry, T., Labar, D., Gilmartin, R., Labiner, D., Osorio, I., Ristanovic, R., Jones, J., … Heck, C. (2000). Prospective long-term study of vagus nerve stimulation for the treatment of refractory seizures (E04). Epilepsia.

Related studies in Epilepsy

Summary by Vagus Research. Always consult the primary source for the authoritative record.

Stay Current with the Research

Join researchers and practitioners exploring the science of vagus nerve stimulation. Receive curated research summaries and evidence updates.

No spam. Unsubscribe at any time. We respect your privacy.